Atorvastatin-induced necrotizing autoimmune myositis
نویسندگان
چکیده
منابع مشابه
Atorvastatin-induced necrotizing autoimmune myositis
The general aim of this study was to evaluate the disease spectrum in patients presenting with a pure polymyositis (pPM) phenotype. Specific objectives were to characterize clinical features, autoantibodies (aAbs), and membrane attack complex (MAC) in muscle biopsies of patients with treatment-responsive, statin-exposed necrotizing autoimmune myositis (NAM). Patients from the Centre hospitalier...
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A 76-year-old man with a history of two prior strokes complicated by residual mild cognitive impairment, atrial fibrillation, coronary artery disease, diabetes mellitus type 2, congestive heart failure, dyslipidemia, and stage 3 chronic kidney disease was admitted for failure to thrive and functional decline. Two months prior, he had been briefly hospitalized for fatigue and inability to walk. ...
متن کاملLaminin-induced autoimmune myositis in rats.
The present study aimed to examine if immunization with laminin causes myositis in rats and whether the pathologic findings mirror human polymyositis and dermatomyositis. Rats were immunized with an emulsion of laminin and complete Freund's adjuvant. As a result, muscle fiber necrosis with infiltrating macrophages was frequently observed and mononuclear cells were observed in the endomysium. Th...
متن کاملMyositis, Pyomyositis, and Necrotizing Fasciitis
Skin and soft-tissue infections (SSTIs) are common in children and usually are recognized easily and treated, with few residual long-term problems. However, although rare, myositis, pyomyositis, and necrotizing fasciitis soft-tissue infections can be difficult to diagnose in their early stages and despite appropriate antibiotic therapy are associated with substantial morbidity and mortality. Th...
متن کاملA case report of autoimmune necrotizing myositis presenting as dysphagia and neck swelling
BACKGROUND Severe dysphagia may occur in the immune mediated necrotizing myopathies (IMNM). Neck swelling and severe dysphagia as the initial symptoms upon presentation has not been previously described. CASE PRESENTATION A 55-year-old male with a 4 week history of neck swelling, fatigue, dysphagia, myalgias, night sweats, and cough was admitted for an elevated CK. He underwent extensive infe...
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ژورنال
عنوان ژورنال: Medicine
سال: 2017
ISSN: 0025-7974
DOI: 10.1097/md.0000000000005694